| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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nadidephosphate;B-NICOTINAMIDEADENINEDINUCLEOTIDE*PHOSPHATEFREE;β-nicotinamideadeninedinucleotidephosphatehydrate;B-NICOTINAMIDEADENINEDINUCLEOTIDEPHOSPHATE,HYDRATE;[(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-[[[Chemicalbook[(2R,3S,4R,5R)-5-(5-carbamoylpyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonicacid;TPN;TPNH;TRIPHOSPHOPYRIDINENUCLEOTIDE
NAD + plays several important roles in metabolism. As a coenzyme in redox reaction, as the afterbody of ADP ribose part in ADP ribosylation reaction, as the precursor of cyclic ADP ribose, a second messenger molecule, and as the substrate of bacterial DNA ligase and group, it is called silencing enzyme, which uses NAD + to remove acetyl group from protein. In addition to metabolic function, NAD + appears as adenine nucleotide, which can spontaneously release cells through regulatory mechanism, so it can play an important extracellular role.
NAD + is an energy providing molecule found in each cell of the body. It is used for metabolism, construction of new cells, resistance to free radicals and DNA damage, and sends signals in cells. It enables mitochondria to convert the food we eat into energy that our body needs to maintain all its functions. We also need to "turn off" genes that accelerate the aging process. NAD + is vital to life. Healthy mitochondrial function is an important part of human aging. Our bodies have the ability to make NAD + from the components of the food we eat. Studies on experimental animals and populations show that the level of NAD + decreases significantly with age. This decline puts us at greater risk of nerve and muscle degeneration, decreased metabolic health of the heart, and repair and elasticity. Scientists from famous research institutions have been studying NAD + enhancement strategy as a treatment for degenerative diseases related to aging. Studies have shown that NAD + plays a unique role in muscle and tissue protection, and also improves the life cycle.
1. In recent years, basic and clinical studies have confirmed that oxidative stress injury is one of the main pathogenesis of diabetic nephropathy. Transgenic technology can significantly improve renal damage in diabetic nephropathy by overexpressing renal antioxidant enzymes, such as superoxide dismutase or catalase. Research basis and current situation based on existing technology.
2, to provide new pharmaceutical uses of nicotinamide adenine dinucleotide phosphate, specifically involving the use of compound nicotinamide adenine dinucleotide phosphate NADP in the preparation of drugs for the prevention and treatment of diabetic nephropathy.
3. In vitro cell experiments and animal experiments confirmed that the NADP can reduce the damage of high glucose to vascular endothelial cells and improve the renal damage of diabetic mice, and can further be used for the preparation of drugs for the prevention and treatment of diabetic nephropathy.
| Product Name: | NADP(Triphosphopyridine nucleotide) |
| Chemical name: | β-nicotinamide adenine dinucleotide phosphate hydrate |
| CAS No.: | 53-59-8 |
| Molecular formula: | C21H28N7O17P3 |
| Appearance: | White Powder |
| Storage: | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Shelf life: | 2 years |
| Package: | 25kgs/drum, 1kg/Aluminum foil bags |
Shanghai NORKY PHARMACEUTICAL Co., Ltd., founded in 2006, is a leading manufacturer and supplier of Active Pharmaceutical Ingredients(APIs) and intermediates with a uniquely broad spectrum of innovative products and high quality. We are active in the development, manufacturing and
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