Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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OSTEOPONTIN,GSTFUSION;)-1-beta-d-ribofuranosylpyridiniumhydroxide,innersalt;adenine-nicotinamidedinucleotide;adenosine5'-(trihydrogendiphosphate),p'.fwdarw.'-esterwith3-(aminChemicalbookocarbonyl;Adenosine5'-(trihydrogendiphosphate),P'.fwdarw.5'-esterwith3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium,innersalt;beta-diphosphopyridine;cozymasei;enzopride
Nicotinamide adenine dinucleotide participates in a variety of physiological activities, such as cellular material metabolism, energy synthesis, cellular DNA repair and so on. In a healthy state, the concentration of nicotinamide adenine dinucleotide in human body is stable and maintains the normal function of various cells. The concentration of nicotinamide adenine dinucleotide in the body determines the process and degree of cell aging. The decrease of concentration will accelerate the process of cell aging.
Studies have shown that NAD + has a protective effect on renal infarction caused by ischemic surgery, and can significantly reduce the levels of serum urea nitrogen and creatinine; NAD + has a protective effect on renal tubular injury caused by ischemic surgery. NAD + (nicotinamide adenine dinucleotide, NAD +) can effectively protect the kidney injury caused by renal ischemia. NAD + has important application value in the preparation of drugs for the prevention and treatment of renal ischemic injury.
In addition, nicotinamide adenine dinucleotide has certain application in the preparation of drugs for the treatment of inflammatory pain. NAD + participates in the regulation of inflammatory pain induced by formalin and complete Freund's adjuvant (CFA) through NAD + dependent deacetylases SIRT1 and sirt2, while SIRT1 and sirt2 participate in the inhibitory effect of NAD + on inflammatory pain through different mechanisms, so as to achieve the analgesic effect on inflammatory pain. Nicotinamide adenine dinucleotide is also used in the preparation of drugs for the prevention and treatment of liver injury induced by chemotherapeutic drug adriamycin hydrochloride. NAD + can not only effectively prevent and treat liver injury caused by chemotherapeutic drug adriamycin hydrochloride, but also find that NAD + can effectively kill neuroglial tumor cells, neuronal tumor cells, gastric cancer tumor cells Renal cell carcinoma cells or breast cancer cells have no killing effect on normal primary cells.
USES & EFFECTIVENESS
1. It is an essential coenzyme in organisms. It is used in biochemical research, clinical diagnosis, clinical drugs and drug research.
2. Coenzyme drugs. Clinically, it is mainly used in the adjuvant treatment of coronary heart disease, which can improve the symptoms of chest tightness and angina pectoris. Adverse reactions occasionally include dry mouth, dizziness, nausea, etc.
3. Participate in energy metabolism and material metabolism in the body, which is conducive to cell repair and renewal. For the treatment of coronary heart disease, myocarditis, leucopenia and other diseases.
Product Name: | NAD(Nicotinamide Adenine Dinucleotide) |
Chemical name: | adenosine5'-(trihydrogendiphosphate) |
CAS No.: | 53-84-9 |
Molecular formula: | C21H27N7O14P2 |
Appearance: | White Powder |
Storage: | -20°C |
Shelf life: | 2 years |
Package: | 25kgs/drum, 1kg/Aluminum foil bags |
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